There are a couple of adjustment options you would have on a 5 axis machine. If your wanting to adjust the depth of tool as it cuts, you can apply a Tool call to your NC program along with G47/G46 (Length comp ON/OFF), then place a desired comp value in the LENGTH field in tool management for the specific tool being used. This will allow a global adjustment for tool length at whatever angle the machine is cutting. Another commonly used method of adjustment for a 5 axis machine would be to use the G92 code. The G92 code allows you to make desired adjusts to various cutout locations within a part. For example, the following example shows moving the "X" location of a cut out positive by .1". This would be in an absolute type program (G90):
(** Original program code **)
G0 X24.5 Y 36.00 Z-12.00 (index to cutout)
(** Updated program code **)
G0 X24.6 Y 36.00 Z-12.00 (Adjusted index to cutout)
G92 X24.5 (Original value for X)
( At this point, the absolute program would run with an adjustment of .1 in the X axis, until the program is edited or adjusted again )
I hope this helps.